HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: PABP3 (Q9H361)
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)
Gene: PABPC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 631
+	Hs
		516541 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		1031352 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		1116304 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PAP1L_HUMAN (1-623): 9.42e-165: 486: 64.97
+	Hs
		516689 PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		516495 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		516339 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		516568 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		403212 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		582322 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		NUCL_HUMAN (2-89): 4.1e-19: 93.7: 31.82
+	At
		285476 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP2_ARATH (2-298): 3.65e-68: 235: 28.85
+	At
		790116 LRP6C_ARATH (12-249): 1.53e-49: 179: 23.14		PABP2_ARATH (2-298): 3.65e-68: 235: 28.85
+	Sc
		376709 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		PABP_YEAST (2-289): 1.72e-65: 226: 30.82
+	At
		285478 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP8_ARATH (187-378): 1.32e-30: 129: 29.38
+	Hs
		1174835 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		PABP5_HUMAN (6-179): 8.16e-39: 149: 23.16
+	Hs
		516635 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		PABP5_HUMAN (6-179): 8.16e-39: 149: 23.16
+	Hs
		403080 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		NUCL_HUMAN (2-89): 4.1e-19: 93.7: 31.82
+	Hs
		516355 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		NUCL_HUMAN (2-89): 4.1e-19: 93.7: 31.82
+	Hs
		474021 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PAB4L_HUMAN (285-371): 2.45e-11: 67.9: 26.97