HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 2581
+	Hs
		516702 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		1059656 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		151420 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CHD1_HUMAN (530-1808): 0: 828: 27.06
+	Hs
		1018458 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		516483 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		151496 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CHD2_HUMAN (373-1741): 0: 803: 25.76
+	Hs
		1018678 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018715 RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1031332 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		516522 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1059849 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1018540 LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018502 ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1059904 RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1059683 LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1059636 ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1109047 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CHD9_HUMAN (2104-2481): 1.87e-106: 385: 29.62
+	Hs
		1116404 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CHD6_HUMAN (1354-2489): 1.68e-106: 385: 14.08
+	Hs
		1116598 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CHD7_HUMAN (7-828): 2.19e-22: 108: 8.97