HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26725010, 29845934, 33961781, 35271311, 25470060
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0097322 - 7SK snRNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 783
+	Hs
		1116497 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1116430 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134068 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571479 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		181706 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DDX3Y_HUMAN (5-581): 7.35e-132: 408: 23.48
+	Hs
		403349 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		516711 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1316899 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1344127 RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		757639 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		134018 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		133858 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		134095 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		1308860 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		134141 LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571585 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Sc
		624057 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		DBP2_YEAST (77-561): 8.25e-130: 399: 25.46
+	Hs
		1271680 RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		516391 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Sc
		376580 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		DED1_YEAST (196-541): 2.98e-56: 205: 37.98