HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: CILK1 (Q9UPZ9)
Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Ciliogenesis associated kinase 1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)
Gene: CILK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 632
+	Hs
		595747 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		MAK_HUMAN (1-632): 2.41e-166: 490: 54.39
+	Hs
		625477 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK2_HUMAN (1-290): 1.28e-143: 420: 38.91
+	Hs
		960098 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK3_HUMAN (1-295): 6.17e-142: 416: 38.59
+	Hs
		414946 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK1_HUMAN (1-289): 3.13e-136: 401: 39.93
+	Hs
		960291 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK5_HUMAN (1-290): 1.44e-131: 389: 33.79
+	Hs
		960440 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK17_HUMAN (1-289): 7.71e-59: 207: 38.49
+	Hs
		403088 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		CDK2_HUMAN (1-290): 1.28e-143: 420: 38.91
+	Hs
		516362 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		CDK2_HUMAN (1-290): 1.28e-143: 420: 38.91
+	Hs
		414931 ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50		CDK1_HUMAN (1-289): 3.13e-136: 401: 39.93
+	At
		1321248 PABP8_ARATH (2-127): 5.76e-15: 80: 11.91		CDKD2_ARATH (1-333): 3.83e-123: 370: 36.42
+	Dm
		582590 SXL_DROME (59-259): 1.13e-24: 107: 20.29		CDK2_DROME (1-285): 2.83e-56: 194: 38.33