HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26725010, 29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0017070 - U6 snRNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 95
+	Hs
		1116658 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		LSM4_HUMAN (1-87): 3.25e-32: 110: 32.58
+	Hs
		912309 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		912652 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		911859 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		403161 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		403163 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		403160 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Sc
		704892 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		LSM4_YEAST (1-83): 6.73e-22: 85.7: 22.83
+	Sc
		376759 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		LSM2_YEAST (1-95): 2.94e-31: 106: 63.16
+	Sc
		376804 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		LSM4_YEAST (1-83): 6.73e-22: 85.7: 22.83
+	Hs
		911850 ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43