HitPredict

Interactor 1: PD5AB (Q4KLU7)
Sister chromatid cohesion protein PDS5 homolog A-B
Gene: pds5a-b

Interactor 2: Q8AW91 (Q8AW91)
Structural maintenance of chromosomes protein
Gene: smc3.L

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15855230
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007064 - mitotic sister chromatid cohesion GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1323 Xl			1 1217
+	Xl
		292739 PD5AA_XENLA (1-1323): 0: 1760: 99.62		SMC3_XENLA (1-1217): 3.66e-127: 422: 99.18
+	Hs
		1100586 PDS5A_HUMAN (1-1323): 0: 1691: 86.56		SMC3_HUMAN (1-1217): 3.79e-127: 422: 96.71
+	Mm
		93885 E9QPI5_MOUSE (1-1323): 0: 1659: 86.70		SMC3_MOUSE (1-1217): 2.26e-127: 423: 96.80
+	Xl
		292729 PD5AB_XENLA (1-1323): 0: 1760: 100.00		SMC1A_XENLA (2-1211): 3.35e-74: 271: 15.56
+	Xl
		292730 PD5AA_XENLA (1-1323): 0: 1760: 99.62		SMC1A_XENLA (2-1211): 3.35e-74: 271: 15.56
+	Xl
		292740 PD5BB_XENLA (15-1317): 0: 1597: 66.96		SMC3_XENLA (1-1217): 3.66e-127: 422: 99.18
+	Xl
		1115499 PD5BA_XENLA (15-1317): 0: 1581: 66.52		Q8AW91_XENLA (1-1217): 5.12e-130: 430: 100.00
+	Xl
		292738 PD5BA_XENLA (15-1317): 0: 1581: 66.52		SMC3_XENLA (1-1217): 3.66e-127: 422: 99.18
+	Hs
		1345702 PDS5B_HUMAN (15-1313): 0: 1569: 67.14		SMC3_HUMAN (1-1217): 3.79e-127: 422: 96.71
+	Hs
		1057273 PDS5A_HUMAN (1-1323): 0: 1691: 86.56		SMC1A_HUMAN (2-1211): 3.37e-79: 286: 15.88
+	Mm
		93884 E9QPI5_MOUSE (1-1323): 0: 1659: 86.70		SMC1A_MOUSE (2-1211): 2.26e-79: 287: 15.88
+	Mm
		1149127 PDS5A_MOUSE (1-1323): 0: 1640: 86.40		SMC1A_MOUSE (2-1211): 2.26e-79: 287: 15.88
+	Hs
		1057405 PDS5B_HUMAN (15-1313): 0: 1569: 67.14		SMC1A_HUMAN (2-1211): 3.37e-79: 286: 15.88
+	Mm
		1118817 PDS5B_MOUSE (15-1317): 0: 1565: 66.69		SMC1A_MOUSE (2-1211): 2.26e-79: 287: 15.88
+	Xl
		292728 PD5BA_XENLA (15-1317): 0: 1581: 66.52		SMC1A_XENLA (2-1211): 3.35e-74: 271: 15.56
+	Sp
		193880 PDS5_SCHPO (26-1154): 0: 904: 21.36		SMC3_SCHPO (1-1212): 3.62e-90: 318: 39.03
+	Sp
		293288 PDS5_SCHPO (26-1154): 0: 904: 21.36		SMC1_SCHPO (2-1204): 7.59e-71: 261: 15.36
+	Sc
		810772 PDS5_YEAST (28-1135): 0: 850: 18.32		SMC3_YEAST (1-1217): 4.95e-85: 304: 29.88
+	Sc
		700799 PDS5_YEAST (28-1135): 0: 850: 18.32		SMC1_YEAST (2-1204): 4.31e-67: 249: 17.45
+	Hs
		69118 A9IYQ1_HUMAN (1049-1313): 1.05e-63: 220: 29.33		SMC1A_HUMAN (2-1211): 3.37e-79: 286: 15.88