HitPredict

Interactor 1: Q4KMX6 (Q4KMX6)
ANAPC7 protein
Gene: ANAPC7

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	TPR_16~WD40
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 564 Hs			1 496
+	Sc
		561125 CDC23_YEAST (36-520): 2.81e-62: 217: 12.20		CDH1_YEAST (44-496): 7.57e-103: 320: 37.81
+	Sc
		454922 CDC16_YEAST (1-520): 3.65e-58: 210: 13.86		CDH1_YEAST (44-496): 7.57e-103: 320: 37.81
+	Sp
		140409 CUT9_SCHPO (8-520): 1.55e-53: 194: 13.74		SRW1_SCHPO (28-495): 2.81e-94: 298: 41.41
+	Hs
		903589 APC7_HUMAN (1-564): 2.45e-106: 332: 100.00		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1356137 APC7_HUMAN (1-564): 2.45e-106: 332: 100.00		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Mm
		1351677 APC7_MOUSE (1-564): 4.44e-104: 326: 98.23		FZR1_MOUSE (319-495): 2.95e-25: 110: 18.68
+	Hs
		1017459 APC7_HUMAN (1-564): 2.45e-106: 332: 100.00		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Mm
		1337483 APC7_MOUSE (1-564): 4.44e-104: 326: 98.23		CDC20_MOUSE (395-494): 5.83e-11: 66.5: 16.67
+	Sc
		454920 CDC16_YEAST (1-520): 3.65e-58: 210: 13.86		AMA1_YEAST (144-474): 4.63e-42: 160: 33.25
+	At
		71753 CDC16_ARATH (6-521): 7.64e-60: 209: 16.89		CDC21_ARATH (334-495): 4.51e-28: 118: 19.08
+	At
		71744 CDC16_ARATH (6-521): 7.64e-60: 209: 16.89		FZR3_ARATH (315-495): 1.15e-19: 93.5: 18.48
+	Hs
		174768 OGT1_HUMAN (14-405): 3.47e-51: 191: 11.39		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	At
		71746 CDC16_ARATH (6-521): 7.64e-60: 209: 16.89		FZR1_ARATH (319-495): 8.99e-18: 87.7: 21.67
+	Sc
		561112 CDC23_YEAST (36-520): 2.81e-62: 217: 12.20		CDC20_YEAST (319-488): 5.34e-14: 76.2: 18.50
+	Hs
		175177 OGT1_HUMAN (14-405): 3.47e-51: 191: 11.39		TBL1R_HUMAN (98-260): 6.38e-22: 100: 13.22
+	Sc
		454896 CDC16_YEAST (1-520): 3.65e-58: 210: 13.86		CDC20_YEAST (319-488): 5.34e-14: 76.2: 18.50
+	Sp
		784811 CUT9_SCHPO (8-520): 1.55e-53: 194: 13.74		SLP1_SCHPO (380-494): 2.87e-11: 67.6: 20.34
+	Hs
		672800 CDC27_HUMAN (271-557): 8.17e-34: 138: 11.68		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Rn
		1118803 CDC27_RAT (271-557): 3.97e-34: 139: 12.03		CDC20_RAT (395-494): 5.94e-11: 66.5: 16.67
+	Hs
		672820 CDC27_HUMAN (271-557): 8.17e-34: 138: 11.68		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67