Interactor 1: Q4KSH6 (Q4KSH6)
mitogen-activated protein kinase kinase (EC 2.7.12.2)
Gene: Map2k4

Interactor 2: M3K1 (Q62925)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)
Gene: Map3k1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17568772
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005524 - ATP binding
GO:0007254 - JNK cascade
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 397
Rn

1 1493
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Last updated: 15 Jul 2024