HitPredict

Interactor 1: Q4LE60 (Q4LE60)
TNPO2 variant protein
Gene: TNPO2

Interactor 2: PD1L1 (Q9NZQ7)
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274)
Gene: CD274

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1051 Hs			1 290
+	Hs
		1117739 Q4LE60_HUMAN (1-1051): 0: 852: 100.00		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		1273232 TNPO1_HUMAN (158-1051): 0: 659: 84.69		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1166522 TNPO1_HUMAN (158-1051): 0: 659: 84.69		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		1273203 TNPO1_HUMAN (158-1051): 0: 659: 84.69		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		1060948 IMB1_HUMAN (175-1047): 3.71e-90: 310: 16.08		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		312409 IPO7_HUMAN (175-1050): 9.67e-88: 306: 14.53		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		178283 IPO8_HUMAN (174-1007): 8.66e-87: 304: 14.94		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		874604 XPO2_HUMAN (168-1050): 4.6e-79: 281: 13.71		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1060791 IMB1_HUMAN (175-1047): 3.71e-90: 310: 16.08		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		312303 IPO7_HUMAN (175-1050): 9.67e-88: 306: 14.53		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		178195 IPO8_HUMAN (174-1007): 8.66e-87: 304: 14.94		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		312358 IPO7_HUMAN (175-1050): 9.67e-88: 306: 14.53		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		874565 XPO2_HUMAN (168-1050): 4.6e-79: 281: 13.71		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		127391 IPO5_HUMAN (116-1050): 4.02e-39: 160: 14.11		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		155653 TNPO2_HUMAN (149-761): 3.45e-26: 118: 13.19		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		155590 TNPO2_HUMAN (149-761): 3.45e-26: 118: 13.19		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		155624 TNPO2_HUMAN (149-761): 3.45e-26: 118: 13.19		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		155541 TNPO2_HUMAN (149-761): 3.45e-26: 118: 13.19		CD80_HUMAN (28-259): 6.01e-30: 116: 21.07