HitPredict

Interactor 1: Q4LE69 (Q4LE69)
1-phosphatidylinositol 4-kinase (EC 2.7.1.67)
Gene: PIK4CA

Interactor 2: C5AR2 (Q9P296)
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
Gene: C5AR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2121 Hs			1 337
+	Hs
		598949 Q4LE69_HUMAN (1-2121): 0: 2752: 100.00		FPR1_HUMAN (34-326): 2.06e-75: 237: 27.85
+	Hs
		598925 PI4KA_HUMAN (49-2121): 0: 2740: 100.00		FPR1_HUMAN (34-326): 2.06e-75: 237: 27.85
+	Hs
		723312 Q4LE69_HUMAN (1-2121): 0: 2752: 100.00		APJ_HUMAN (26-336): 6.02e-67: 216: 23.21
+	Hs
		723280 PI4KA_HUMAN (49-2121): 0: 2740: 100.00		APJ_HUMAN (26-336): 6.02e-67: 216: 23.21
+	Hs
		723045 Q4LE69_HUMAN (1-2121): 0: 2752: 100.00		OPRM_HUMAN (11-333): 1.48e-61: 203: 18.29
+	Hs
		787693 PI4KA_HUMAN (49-2121): 0: 2740: 100.00		C5AR2_HUMAN (1-337): 1.47e-65: 211: 100.00
+	Hs
		723014 PI4KA_HUMAN (49-2121): 0: 2740: 100.00		OPRM_HUMAN (11-333): 1.48e-61: 203: 18.29
+	Hs
		787363 PK3CB_HUMAN (1465-2118): 7.11e-140: 467: 18.78		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		822537 PK3CG_HUMAN (1522-2119): 7.16e-133: 448: 19.56		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Mm
		936867 PK3CG_MOUSE (1522-2119): 4.65e-131: 443: 19.87		CXCR4_MOUSE (2-298): 6.63e-71: 226: 24.60