HitPredict

Interactor 1: ARP3 (Q4V7C7)
Actin-related protein 3 (Actin-like protein 3)
Gene: Actr3

Interactor 2: WIPF1 (Q6IN36)
WAS/WASL-interacting protein family member 1 (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16990791
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0001726 - ruffle GO:0003779 - actin binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 418 Rn			1 487
+	Rn
		892234 ACTB_RAT (1-414): 0: 544: 35.42		WIPF1_RAT (1-487): 1.69e-31: 128: 100.00
+	Hs
		554290 ACTA_HUMAN (3-414): 0: 531: 35.35		MUC1_HUMAN (9-479): 5.07e-30: 126: 12.03
+	Hs
		206686 ACTG_HUMAN (1-414): 0: 543: 35.18		WIPF1_HUMAN (1-487): 3.26e-25: 110: 79.32
+	Hs
		891920 ACTB_HUMAN (1-414): 0: 544: 35.42		WIPF2_HUMAN (14-487): 5.23e-24: 106: 36.35
+	Hs
		929941 ACTG_HUMAN (1-414): 0: 543: 35.18		WIPF2_HUMAN (14-487): 5.23e-24: 106: 36.35
+	Hs
		891932 ACTB_HUMAN (1-414): 0: 544: 35.42		CTTB2_HUMAN (76-463): 4.46e-20: 96: 15.89
+	Hs
		932278 ACTC_HUMAN (3-414): 0: 533: 35.35		WIPF2_HUMAN (14-487): 5.23e-24: 106: 36.35
+	Hs
		891853 ACTB_HUMAN (1-414): 0: 544: 35.42		SRCAP_HUMAN (53-485): 1.91e-10: 65.6: 11.69
+	Hs
		929905 ACTG_HUMAN (1-414): 0: 543: 35.18		SRCAP_HUMAN (53-485): 1.91e-10: 65.6: 11.69
+	Hs
		891942 ACTB_HUMAN (1-414): 0: 544: 35.42		CBP_HUMAN (78-474): 7.6e-09: 60.6: 11.47
+	Hs
		203220 ACTC_HUMAN (3-414): 0: 533: 35.35		SYNJ1_HUMAN (134-486): 2.91e-11: 68.3: 15.97
+	Hs
		932219 ACTC_HUMAN (3-414): 0: 533: 35.35		SRCAP_HUMAN (53-485): 1.91e-10: 65.6: 11.69
+	Hs
		932156 ACTC_HUMAN (3-414): 0: 533: 35.35		MDC1_HUMAN (14-472): 4.01e-10: 64.8: 11.80
+	Hs
		915464 ACTA_HUMAN (3-414): 0: 531: 35.35		CBP_HUMAN (78-474): 7.6e-09: 60.6: 11.47