HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: KIBRA (Q8IX03)
Protein KIBRA (HBeAg-binding protein 3) (Kidney and brain protein) (KIBRA) (WW domain-containing protein 1)
Gene: WWC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	24366813, 28720576, 33961781, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Hs			1 1113
+	Hs
		1220065 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		KIBRA_HUMAN (1-1113): 0: 842: 100.00
+	Hs
		1220103 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		KIBRA_HUMAN (1-1113): 0: 842: 100.00
+	Hs
		1119034 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		NED4L_HUMAN (656-807): 2.04e-33: 141: 15.09
+	Hs
		1119026 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		ITCH_HUMAN (2-164): 5.57e-30: 130: 22.94
+	Hs
		1119076 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWOX_HUMAN (5-113): 1.68e-31: 130: 29.46
+	Hs
		1119052 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWP1_HUMAN (2-162): 9.09e-26: 117: 25.77
+	Hs
		1119035 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		MAGI1_HUMAN (36-163): 3.73e-13: 76.5: 25.95
+	Hs
		125503 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWP2_HUMAN (35-303): 1.01e-10: 68.2: 16.36
+	Hs
		808669 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		YAP1_HUMAN (37-159): 1.07e-10: 67.6: 19.84
+	Hs
		808151 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		NEDD4_HUMAN (26-161): 2.24e-09: 64: 21.32
+	Mm
		809078 AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11		YAP1_MOUSE (1-56): 2.33e-11: 69.5: 41.67
+	Hs
		1222263 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		NED4L_HUMAN (656-807): 2.04e-33: 141: 15.09
+	Hs
		1132674 FKB15_HUMAN (184-1080): 4.84e-41: 166: 14.92		WWOX_HUMAN (5-113): 1.68e-31: 130: 29.46
+	Hs
		1349059 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		WWOX_HUMAN (5-113): 1.68e-31: 130: 29.46
+	Hs
		1309697 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		SYT3_HUMAN (651-792): 3.79e-27: 120: 14.09
+	Hs
		1222264 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		MAGI1_HUMAN (36-163): 3.73e-13: 76.5: 25.95
+	Hs
		1199783 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		MAGI2_HUMAN (42-196): 2.85e-12: 73.4: 23.42
+	Hs
		125569 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		WWP2_HUMAN (35-303): 1.01e-10: 68.2: 16.36
+	Hs
		808761 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		YAP1_HUMAN (37-159): 1.07e-10: 67.6: 19.84
+	Hs
		808183 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		NEDD4_HUMAN (26-161): 2.24e-09: 64: 21.32