HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	27173435, 33961781, 35271311, 24366813, 19615732
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1084 Hs			1 89
+	Hs
		928323 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		928379 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		1222261 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00
+	Hs
		928532 AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		1291337 AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00
+	Hs
		148656 CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		928294 DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		1051400 DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00