HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: LZTS1 (Q9Y250)
Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1)
Gene: LZTS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1084 Hs			1 596
+	Hs
		1119042 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		LZTS2_HUMAN (1-596): 1.2e-37: 150: 34.66
+	Hs
		1119108 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		MTCL1_HUMAN (8-570): 1.12e-25: 115: 11.74
+	Hs
		1118957 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		CCD18_HUMAN (259-552): 2.97e-11: 68.8: 21.59
+	Hs
		57699 A2BDD9_HUMAN (412-1084): 1.21e-39: 159: 99.70		LZTS1_HUMAN (1-596): 1.46e-59: 210: 100.00
+	Rn
		655923 DCTN1_RAT (279-757): 1.63e-38: 158: 15.10		DCTN1_RAT (182-587): 4.93e-38: 152: 14.35
+	Hs
		1310222 CE164_HUMAN (20-1032): 2.66e-35: 148: 11.99		LZTS2_HUMAN (1-596): 1.2e-37: 150: 34.66
+	Hs
		61869 CC88B_HUMAN (39-1023): 2.68e-32: 138: 11.95		TSC1_HUMAN (7-587): 1.97e-34: 141: 11.77
+	Hs
		1137871 MRCKA_HUMAN (257-924): 1.39e-36: 152: 10.38		MRCKA_HUMAN (329-595): 7.21e-19: 93.5: 18.28
+	Hs
		522657 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		MYH7_HUMAN (170-595): 5.36e-13: 74.6: 12.93
+	Hs
		528435 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		MYH8_HUMAN (142-563): 7.37e-13: 74.2: 11.19
+	Hs
		502933 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		MYH3_HUMAN (234-596): 4.99e-12: 71.5: 14.87
+	Dm
		803043 Q9W179_DROME (360-971): 9.04e-42: 169: 15.18		MOEH_DROME (258-541): 3.91e-10: 64.5: 20.48
+	Hs
		1078919 ITSN2_HUMAN (192-932): 2.36e-30: 132: 10.74		ITSN1_HUMAN (1-580): 2.62e-20: 98.1: 12.58
+	Hs
		1137917 MRCKA_HUMAN (257-924): 1.39e-36: 152: 10.38		MRCKB_HUMAN (397-592): 5.76e-13: 74.2: 14.07
+	Hs
		1137872 MRCKA_HUMAN (257-924): 1.39e-36: 152: 10.38		CP135_HUMAN (242-539): 1.03e-10: 66.8: 20.19
+	Rn
		222472 MRCKA_RAT (432-960): 6.53e-29: 128: 13.95		MRCKA_RAT (329-596): 2.89e-17: 88: 17.83
+	Hs
		1145989 CE164_HUMAN (20-1032): 2.66e-35: 148: 11.99		CP135_HUMAN (242-539): 1.03e-10: 66.8: 20.19
+	Rn
		222476 MRCKA_RAT (432-960): 6.53e-29: 128: 13.95		MRCKB_RAT (170-510): 9.99e-09: 60.7: 11.40
+	Rn
		1186812 MRCKB_RAT (245-687): 6.55e-20: 98.5: 10.95		MRCKB_RAT (170-510): 9.99e-09: 60.7: 11.40