HitPredict

Interactor 1: PAN2 (Q504Q3)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21984185
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 1962
+	Hs
		1119516 PAN2_HUMAN (1-1202): 0: 1136: 100.00		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		1119487 PAN2_HUMAN (1-1202): 0: 1136: 100.00		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Hs
		1119453 PAN2_HUMAN (1-1202): 0: 1136: 100.00		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Dm
		52499 PAN2_DROME (5-1183): 0: 820: 39.07		GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88
+	Hs
		1270763 UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		62113 UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02		F186A_HUMAN (1013-1755): 1.33e-10: 69.1: 11.40
+	Hs
		998956 UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		259280 UBP12_HUMAN (516-858): 4.44e-83: 277: 12.26		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05