HitPredict

Interactor 1: PAN2 (Q504Q3)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19615732, 23398456
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 543
+	Hs
		826689 PAN2_HUMAN (1-1202): 0: 1136: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821241 PAN2_HUMAN (1-1202): 0: 1136: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573289 PAN2_HUMAN (1-1202): 0: 1136: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843227 PAN2_HUMAN (1-1202): 0: 1136: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		171824 WDR46_HUMAN (35-483): 2.12e-94: 317: 12.19		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		69613 B0UZZ8_HUMAN (35-483): 2.12e-94: 317: 12.19		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1306654 KTNB1_HUMAN (44-520): 3.36e-83: 287: 15.07		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		171740 WDR46_HUMAN (35-483): 2.12e-94: 317: 12.19		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		69569 B0UZZ8_HUMAN (35-483): 2.12e-94: 317: 12.19		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Sc
		767373 UTP7_YEAST (35-461): 8e-81: 278: 15.37		TCPH_YEAST (2-542): 0: 587: 62.45
+	Hs
		821392 KTNB1_HUMAN (44-520): 3.36e-83: 287: 15.07		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573530 UBP22_HUMAN (462-854): 5.81e-86: 291: 12.30		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573456 KTNB1_HUMAN (44-520): 3.36e-83: 287: 15.07		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Sc
		760737 UTP7_YEAST (35-461): 8e-81: 278: 15.37		TCPG_YEAST (2-527): 0: 546: 30.68