HitPredict

Interactor 1: Q53FC7 (Q53FC7)
Heat shock 70kDa protein 6 (HSP70B') variant
Gene: Q53FC7

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 1215
+	Hs
		564200 HSP76_HUMAN (1-643): 0: 990: 99.22		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		714086 HS71L_HUMAN (1-643): 0: 981: 78.85		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		504893 HSP7C_HUMAN (4-615): 0: 959: 78.76		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		871814 HSP72_HUMAN (3-643): 0: 945: 77.14		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		564072 HSP76_HUMAN (1-643): 0: 990: 99.22		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		504036 HSP7C_HUMAN (4-615): 0: 959: 78.76		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		504501 HSP7C_HUMAN (4-615): 0: 959: 78.76		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		503771 HSP7C_HUMAN (4-615): 0: 959: 78.76		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		504526 HSP7C_HUMAN (4-615): 0: 959: 78.76		HDA10_HUMAN (85-449): 8.19e-152: 473: 53.53
+	Hs
		177179 HSP7C_HUMAN (4-615): 0: 959: 78.76		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29
+	Dm
		505070 HSP7D_DROME (4-614): 0: 945: 78.89		Q86NK9_DROME (1093-1215): 1.8e-41: 168: 45.97