HitPredict - High confidence protein-protein interactions

Interactor 1: PAR10 (Q53GL7)
Protein mono-ADP-ribosyltransferase PARP10 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 10) (ARTD10) (Poly [ADP-ribose] polymerase 10) (PARP-10)
Gene: PARP10

Interactor 2: PAR10 (Q53GL7)
Protein mono-ADP-ribosyltransferase PARP10 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 10) (ARTD10) (Poly [ADP-ribose] polymerase 10) (PARP-10)
Gene: PARP10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	29515234, 36197986
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PARP~PARP
Common GO terms	GO:0003714 - transcription corepressor activity GO:0003950 - NAD+ ADP-ribosyltransferase activity GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005737 - cytoplasm and 17 others more... GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0006325 - chromatin organization GO:0010629 - negative regulation of gene expression GO:0016779 - nucleotidyltransferase activity GO:0019082 - viral protein processing GO:0019985 - translesion synthesis GO:0032088 - negative regulation of NF-kappaB transcription factor activity GO:0034356 - NAD biosynthesis via nicotinamide riboside salvage pathway GO:0048147 - negative regulation of fibroblast proliferation GO:0070212 - protein poly-ADP-ribosylation GO:0070213 - protein auto-ADP-ribosylation GO:0070530 - K63-linked polyubiquitin modification-dependent protein binding GO:0140297 - DNA-binding transcription factor binding GO:0140804 - NAD+- protein-lysine ADP-ribosyltransferase activity GO:1900045 - negative regulation of protein K63-linked ubiquitination GO:1990404 - NAD+-protein ADP-ribosyltransferase activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	1025
Hs

1	1025

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Last updated: 15 Jul 2024