HitPredict

Interactor 1: KLH22 (Q53GT1)
Kelch-like protein 22
Gene: KLHL22

Interactor 2: KLH13 (Q9P2N7)
Kelch-like protein 13 (BTB and kelch domain-containing protein 2)
Gene: KLHL13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 28514442, 33961781, 19995937, 19615732, 21145461, 30190310
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BTB~BTB, Kelch_1~Kelch_1, Kelch_1~Kelch_3, Kelch_1~Kelch_6
Common GO terms GO:0005829 - cytosol
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0051301 - cell division
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 634
Hs

1 655
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024