HitPredict

Interactor 1: M9MRE1 (M9MRE1)
PDGF- and VEGF-receptor related, isoform K (EC 2.7.10.1)
Gene: Pvr

Interactor 2: M9PAY7 (M9PAY7)
Pi3K21B, isoform C (Pi3K21B, isoform D)
Gene: Pi3K21B

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.80	0.834

Property	Details
Experiments	22068330, 26839216, 27626673, 15457211, 16054027, 17637670
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1500 Dm			1 197
+	Dm
		112231 M9MRE1_DROME (19-1500): 0: 987: 100.00		SRC42_DROME (5-192): 4.49e-56: 186: 20.31
+	Dm
		112209 M9MRE1_DROME (19-1500): 0: 987: 100.00		ABL_DROME (3-191): 1.67e-53: 185: 17.77
+	Dm
		112210 M9MRE1_DROME (19-1500): 0: 987: 100.00		BTKL_DROME (2-192): 5.89e-47: 165: 15.08
+	Dm
		186281 Q8IPG1_DROME (19-1500): 0: 979: 99.20		O18683_DROME (9-136): 3.04e-30: 117: 22.31
+	Dm
		112228 M9MRE1_DROME (19-1500): 0: 987: 100.00		VAV_DROME (24-120): 1.63e-12: 67.1: 27.78
+	Mm
		729715 VGFR1_MOUSE (2-1423): 0: 717: 21.85		PLCG1_MOUSE (5-156): 3.03e-28: 112: 20.83
+	Hs
		433274 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		YES_HUMAN (2-192): 6.47e-60: 197: 17.91
+	Hs
		522826 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		SRC_HUMAN (2-192): 6.32e-59: 194: 18.41
+	Hs
		412062 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		FYN_HUMAN (2-192): 1.28e-58: 193: 19.51
+	Hs
		442785 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		HCK_HUMAN (4-192): 1.17e-57: 191: 20.10
+	Hs
		454802 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		FGR_HUMAN (3-190): 3.17e-56: 187: 19.70
+	Hs
		411619 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		LCK_HUMAN (2-192): 8.98e-56: 185: 21.89
+	Hs
		433624 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		LYN_HUMAN (1-192): 1.77e-55: 184: 17.33
+	Hs
		738170 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		ABL2_HUMAN (5-191): 7.13e-51: 177: 15.98
+	Hs
		337376 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		ABL1_HUMAN (5-191): 2.48e-50: 176: 15.98
+	Hs
		738179 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		BLK_HUMAN (1-190): 6.19e-52: 175: 17.59
+	Hs
		655242 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		P85A_HUMAN (18-132): 4.73e-24: 100: 25.42
+	Hs
		738192 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		GRB2_HUMAN (28-106): 5.43e-11: 61.3: 30.49
+	Hs
		411943 CSF1R_HUMAN (44-584): 1.28e-50: 197: 13.82		FYN_HUMAN (2-192): 1.28e-58: 193: 19.51
+	Hs
		129165 CSF1R_HUMAN (44-584): 1.28e-50: 197: 13.82		P85B_HUMAN (19-149): 1.39e-26: 107: 23.29