HitPredict

Interactor 1: M9MRE1 (M9MRE1)
PDGF- and VEGF-receptor related, isoform K (EC 2.7.10.1)
Gene: Pvr

Interactor 2: CRK (Q9XYM0)
Adapter molecule Crk
Gene: CRK

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	15457211
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1500 Dm			1 271
+	Dm
		112240 M9MRE1_DROME (19-1500): 0: 987: 100.00		Q9VXH3_DROME (5-267): 1.49e-34: 134: 15.48
+	Dm
		112214 M9MRE1_DROME (19-1500): 0: 987: 100.00		GRAP_DROME (204-256): 3.79e-11: 63.1: 20.37
+	Mm
		729715 VGFR1_MOUSE (2-1423): 0: 717: 21.85		PLCG1_MOUSE (2-269): 2.44e-38: 144: 16.51
+	Mm
		729717 VGFR1_MOUSE (2-1423): 0: 717: 21.85		CD2AP_MOUSE (20-163): 9.9e-11: 63.9: 18.07
+	Hs
		738174 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		CRKL_HUMAN (4-267): 5.07e-52: 173: 42.72
+	Hs
		738173 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		CRK_HUMAN (4-266): 2.13e-51: 172: 43.48
+	Hs
		411619 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		LCK_HUMAN (1-235): 1.9e-29: 117: 14.94
+	Hs
		412062 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		FYN_HUMAN (112-239): 9.59e-14: 72.8: 21.21
+	Hs
		738192 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		GRB2_HUMAN (204-256): 1.59e-12: 67: 27.78
+	Hs
		433274 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		YES_HUMAN (179-265): 8.33e-11: 63.9: 15.73
+	Hs
		522826 FLT3_HUMAN (210-1297): 5.01e-163: 520: 19.53		SRC_HUMAN (157-265): 2.41e-10: 62.4: 10.62
+	Hs
		572596 VGFR1_HUMAN (5-489): 5.34e-49: 194: 12.64		CRKL_HUMAN (4-267): 5.07e-52: 173: 42.72
+	Hs
		572583 VGFR1_HUMAN (5-489): 5.34e-49: 194: 12.64		PLCG1_HUMAN (2-269): 1.17e-37: 142: 16.51
+	Hs
		275162 CSF1R_HUMAN (44-584): 1.28e-50: 197: 13.82		GRAP2_HUMAN (4-258): 9.53e-38: 137: 17.67
+	Hs
		411943 CSF1R_HUMAN (44-584): 1.28e-50: 197: 13.82		FYN_HUMAN (112-239): 9.59e-14: 72.8: 21.21
+	Hs
		411995 VGFR1_HUMAN (5-489): 5.34e-49: 194: 12.64		FYN_HUMAN (112-239): 9.59e-14: 72.8: 21.21
+	Hs
		426993 CSF1R_HUMAN (44-584): 1.28e-50: 197: 13.82		GRB2_HUMAN (204-256): 1.59e-12: 67: 27.78
+	Hs
		426975 CSF1R_HUMAN (44-584): 1.28e-50: 197: 13.82		YES_HUMAN (179-265): 8.33e-11: 63.9: 15.73
+	Hs
		426981 CSF1R_HUMAN (44-584): 1.28e-50: 197: 13.82		SRC_HUMAN (157-265): 2.41e-10: 62.4: 10.62
+	Hs
		433247 VGFR1_HUMAN (5-489): 5.34e-49: 194: 12.64		YES_HUMAN (179-265): 8.33e-11: 63.9: 15.73