HitPredict

Interactor 1: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 30209976, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 1191
+	Hs
		1164374 POTEE_HUMAN (3-376): 0: 693: 85.03		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		930010 ACTG_HUMAN (3-376): 0: 595: 91.44		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		933059 ACTS_HUMAN (2-376): 0: 590: 87.47		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1122422 ACTBL_HUMAN (1-376): 0: 616: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		929894 ACTG_HUMAN (3-376): 0: 595: 91.44		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		932993 ACTS_HUMAN (2-376): 0: 590: 87.47		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		554315 ACTBL_HUMAN (1-376): 0: 616: 100.00		MUC1_HUMAN (344-901): 6.29e-21: 102: 9.70
+	Hs
		554290 ACTA_HUMAN (1-376): 0: 588: 87.80		MUC1_HUMAN (344-901): 6.29e-21: 102: 9.70
+	Hs
		1122431 ACTBL_HUMAN (1-376): 0: 616: 100.00		SRCAP_HUMAN (482-817): 8.67e-10: 65.7: 15.61
+	Hs
		932156 ACTC_HUMAN (2-376): 0: 590: 88.27		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		891853 ACTB_HUMAN (3-376): 0: 596: 91.71		SRCAP_HUMAN (482-817): 8.67e-10: 65.7: 15.61
+	Hs
		929905 ACTG_HUMAN (3-376): 0: 595: 91.44		SRCAP_HUMAN (482-817): 8.67e-10: 65.7: 15.61
+	Hs
		891942 ACTB_HUMAN (3-376): 0: 596: 91.71		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		203220 ACTC_HUMAN (2-376): 0: 590: 88.27		SYNJ1_HUMAN (311-744): 1.47e-10: 68.1: 9.19
+	Hs
		932219 ACTC_HUMAN (2-376): 0: 590: 88.27		SRCAP_HUMAN (482-817): 8.67e-10: 65.7: 15.61
+	Hs
		325685 ACTS_HUMAN (2-376): 0: 590: 87.47		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		915464 ACTA_HUMAN (1-376): 0: 588: 87.80		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Sp
		501586 ACT_SCHPO (3-376): 0: 587: 85.29		LKH1_SCHPO (527-814): 6.12e-09: 62.2: 14.78