HitPredict

Interactor 1: HDA10 (Q569C4)
Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10)
Gene: Hdac10

Interactor 2: GRB7 (Q9QZC5)
Growth factor receptor-bound protein 7 (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
Gene: GRB7

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32360748
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 588 Rn			1 535
+	Hs
		1054075 HDAC2_HUMAN (6-352): 1.44e-127: 385: 19.89		GRB7_HUMAN (1-535): 0: 587: 90.11
+	Hs
		1031698 HDAC2_HUMAN (6-352): 1.44e-127: 385: 19.89		GRB10_HUMAN (1-535): 0: 555: 52.88
+	Hs
		1038482 HDAC1_HUMAN (6-352): 6.22e-137: 409: 21.02		RAPH1_HUMAN (4-355): 4.03e-112: 362: 25.00
+	Hs
		412390 HDAC6_HUMAN (3-320): 2.07e-124: 397: 51.41		FYN_HUMAN (372-532): 1.7e-45: 169: 19.05
+	Hs
		433496 HDAC6_HUMAN (3-320): 2.07e-124: 397: 51.41		YES_HUMAN (372-533): 8.44e-45: 167: 20.12
+	Hs
		434052 HDAC6_HUMAN (3-320): 2.07e-124: 397: 51.41		LYN_HUMAN (375-531): 1.97e-42: 160: 20.86
+	Hs
		177182 HDAC3_HUMAN (4-363): 9.51e-130: 388: 20.71		SRC_HUMAN (360-531): 2.51e-41: 158: 22.91
+	Mm
		639460 Q9JM08_MOUSE (4-363): 3.64e-128: 384: 20.71		LYN_MOUSE (375-531): 2.09e-41: 157: 20.86
+	Hs
		880672 HDAC4_HUMAN (2-381): 1.15e-136: 426: 33.25		GRB2_HUMAN (400-516): 2.34e-14: 74: 27.35
+	Hs
		796673 HDAC9_HUMAN (2-356): 5.28e-138: 428: 33.77		KSYK_HUMAN (421-528): 5.74e-12: 70.2: 32.41
+	Hs
		796534 HDAC4_HUMAN (2-381): 1.15e-136: 426: 33.25		KSYK_HUMAN (421-528): 5.74e-12: 70.2: 32.41
+	Hs
		796566 HDAC1_HUMAN (6-352): 6.22e-137: 409: 21.02		KSYK_HUMAN (421-528): 5.74e-12: 70.2: 32.41
+	Hs
		796667 HDAC6_HUMAN (3-320): 2.07e-124: 397: 51.41		KSYK_HUMAN (421-528): 5.74e-12: 70.2: 32.41
+	Hs
		986047 HDAC6_HUMAN (3-320): 2.07e-124: 397: 51.41		PTN11_HUMAN (431-522): 2.09e-11: 68.3: 34.78
+	Hs
		177227 HDAC3_HUMAN (4-363): 9.51e-130: 388: 20.71		KSYK_HUMAN (421-528): 5.74e-12: 70.2: 32.41
+	Hs
		796619 HDAC2_HUMAN (6-352): 1.44e-127: 385: 19.89		KSYK_HUMAN (421-528): 5.74e-12: 70.2: 32.41