HitPredict

Interactor 1: PAN3 (Q58A45)
PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3)
Gene: PAN3

Interactor 2: TNR6C (Q9HCJ0)
Trinucleotide repeat-containing gene 6C protein
Gene: TNRC6C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	21981923, 21984184, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 887 Hs			1 1936
+	Hs
		1123122 PAN3_HUMAN (45-887): 0: 738: 100.00		TNR6A_HUMAN (2-1933): 2.2e-125: 440: 35.43
+	Hs
		1123139 PAN3_HUMAN (45-887): 0: 738: 100.00		TNR6B_HUMAN (18-1920): 9.22e-118: 415: 30.70
+	Dm
		1249008 PAN3_DROME (303-883): 6.43e-120: 384: 43.96		GAWKY_DROME (650-1849): 7.88e-73: 271: 21.24
+	Dm
		87998 D3DMN9_DROME (303-883): 6.35e-120: 384: 43.96		GAWKY_DROME (650-1849): 7.88e-73: 271: 21.24
+	Hs
		229976 NUAK1_HUMAN (464-748): 5.64e-25: 112: 14.98		TARA_HUMAN (67-1697): 1.88e-29: 131: 8.94
+	Hs
		851746 NEK4_HUMAN (488-766): 2e-32: 137: 16.17		SRRM2_HUMAN (269-1785): 4.31e-20: 100: 8.50
+	Hs
		229985 NUAK1_HUMAN (464-748): 5.64e-25: 112: 14.98		SRRM2_HUMAN (269-1785): 4.31e-20: 100: 8.50
+	Hs
		625642 CDK2_HUMAN (491-716): 1.04e-24: 107: 14.52		SRRM2_HUMAN (269-1785): 4.31e-20: 100: 8.50