HitPredict

Interactor 1: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Interactor 2: STYK1 (Q6J9G0)
Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)
Gene: STYK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 422
+	Hs
		438028 HS90B_HUMAN (1-504): 0: 671: 69.93		EPHB1_HUMAN (5-417): 7.24e-127: 391: 19.38
+	Hs
		437838 HS90B_HUMAN (1-504): 0: 671: 69.93		FGFR1_HUMAN (11-417): 2.76e-127: 388: 24.20
+	Hs
		437897 HS90B_HUMAN (1-504): 0: 671: 69.93		FGFR3_HUMAN (10-409): 1.6e-125: 383: 27.01
+	Hs
		437918 HS90B_HUMAN (1-504): 0: 671: 69.93		EPHA2_HUMAN (46-411): 2.25e-121: 377: 21.95
+	Hs
		438029 HS90B_HUMAN (1-504): 0: 671: 69.93		EPHA4_HUMAN (42-417): 8.52e-119: 370: 18.73
+	Hs
		169160 HS90B_HUMAN (1-504): 0: 671: 69.93		MUSK_HUMAN (24-393): 4.95e-119: 368: 22.28
+	Hs
		437895 HS90B_HUMAN (1-504): 0: 671: 69.93		FGFR4_HUMAN (80-392): 2.13e-119: 367: 28.79
+	Hs
		438265 HS90B_HUMAN (1-504): 0: 671: 69.93		STYK1_HUMAN (1-422): 3.03e-124: 367: 100.00
+	Hs
		169159 HS90A_HUMAN (1-504): 0: 655: 62.96		MUSK_HUMAN (24-393): 4.95e-119: 368: 22.28
+	Hs
		437847 HS90B_HUMAN (1-504): 0: 671: 69.93		SRC_HUMAN (90-390): 1.63e-110: 336: 28.95
+	Hs
		411949 HS90B_HUMAN (1-504): 0: 671: 69.93		FYN_HUMAN (92-390): 1.01e-109: 334: 28.33
+	Hs
		437967 HS90B_HUMAN (1-504): 0: 671: 69.93		FRK_HUMAN (83-386): 1.13e-109: 333: 28.25
+	Dm
		365472 HSP83_DROME (1-504): 0: 669: 57.69		SRC42_DROME (76-386): 1.12e-109: 334: 27.89
+	Hs
		433218 HS90B_HUMAN (1-504): 0: 671: 69.93		YES_HUMAN (88-390): 1.93e-108: 331: 28.76
+	Hs
		337314 HS90B_HUMAN (1-504): 0: 671: 69.93		ABL1_HUMAN (143-387): 8.6e-41: 156: 35.34
+	Hs
		69196 HS90B_HUMAN (1-504): 0: 671: 69.93		A9UEZ6_HUMAN (143-387): 1.01e-40: 156: 35.34
+	Hs
		437966 HS90B_HUMAN (1-504): 0: 671: 69.93		ABL2_HUMAN (143-381): 3.74e-40: 155: 36.63
+	Hs
		437946 HS90B_HUMAN (1-504): 0: 671: 69.93		TIE1_HUMAN (120-380): 8.51e-36: 142: 32.96
+	Hs
		337312 HS90A_HUMAN (1-504): 0: 655: 62.96		ABL1_HUMAN (143-387): 8.6e-41: 156: 35.34
+	Hs
		437960 HS90B_HUMAN (1-504): 0: 671: 69.93		CSK_HUMAN (144-386): 2.31e-36: 140: 36.89