HitPredict

Interactor 1: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Interactor 2: PDK1L (Q8N165)
Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1-interacting kinase 1-like)
Gene: PDIK1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 341
+	Hs
		438385 HS90B_HUMAN (1-504): 0: 671: 69.93		STK35_HUMAN (3-332): 1.4e-127: 377: 68.73
+	Hs
		432094 HS90A_HUMAN (1-504): 0: 655: 62.96		STK35_HUMAN (3-332): 1.4e-127: 377: 68.73
+	Hs
		437908 HS90B_HUMAN (1-504): 0: 671: 69.93		CDK2_HUMAN (5-337): 6.66e-114: 334: 21.78
+	Hs
		438381 HS90B_HUMAN (1-504): 0: 671: 69.93		MK15_HUMAN (2-340): 1.49e-110: 334: 21.91
+	Hs
		438075 HS90B_HUMAN (1-504): 0: 671: 69.93		CDK3_HUMAN (5-332): 1.5e-112: 330: 21.22
+	Hs
		438344 HS90B_HUMAN (1-504): 0: 671: 69.93		PDK1L_HUMAN (1-341): 1.05e-110: 327: 100.00
+	Hs
		431549 HS90A_HUMAN (1-504): 0: 655: 62.96		CDK2_HUMAN (5-337): 6.66e-114: 334: 21.78
+	Hs
		432091 HS90A_HUMAN (1-504): 0: 655: 62.96		MK15_HUMAN (2-340): 1.49e-110: 334: 21.91
+	Hs
		431741 HS90A_HUMAN (1-504): 0: 655: 62.96		CDK3_HUMAN (5-332): 1.5e-112: 330: 21.22
+	Hs
		432048 HS90A_HUMAN (1-504): 0: 655: 62.96		PDK1L_HUMAN (1-341): 1.05e-110: 327: 100.00
+	Hs
		414683 HS90A_HUMAN (1-504): 0: 655: 62.96		CDK1_HUMAN (5-338): 1.3e-108: 320: 21.37
+	Hs
		438496 HS90B_HUMAN (1-504): 0: 671: 69.93		STK33_HUMAN (8-325): 6.19e-27: 112: 28.17
+	Hs
		438277 HS90B_HUMAN (1-504): 0: 671: 69.93		ULK3_HUMAN (6-251): 1.66e-19: 90.9: 29.30
+	Hs
		438015 HS90B_HUMAN (1-504): 0: 671: 69.93		NEK4_HUMAN (8-320): 9.2e-19: 89.4: 24.92
+	Hs
		262221 HS90B_HUMAN (1-504): 0: 671: 69.93		ULK1_HUMAN (112-278): 1.48e-18: 89: 33.14
+	Hs
		438350 HS90B_HUMAN (1-504): 0: 671: 69.93		DCLK2_HUMAN (7-251): 3.08e-18: 87.8: 30.00
+	Hs
		431967 HS90A_HUMAN (1-504): 0: 655: 62.96		ULK3_HUMAN (6-251): 1.66e-19: 90.9: 29.30
+	Hs
		431675 HS90A_HUMAN (1-504): 0: 655: 62.96		NEK4_HUMAN (8-320): 9.2e-19: 89.4: 24.92
+	Hs
		262219 HS90A_HUMAN (1-504): 0: 655: 62.96		ULK1_HUMAN (112-278): 1.48e-18: 89: 33.14
+	Hs
		432057 HS90A_HUMAN (1-504): 0: 655: 62.96		DCLK2_HUMAN (7-251): 3.08e-18: 87.8: 30.00