HitPredict

Interactor 1: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Interactor 2: AGO4 (Q9HCK5)
Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4)
Gene: AGO4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 861
+	Hs
		438545 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO4_HUMAN (1-861): 0: 1180: 100.00
+	Hs
		432278 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO4_HUMAN (1-861): 0: 1180: 100.00
+	Hs
		438615 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO1_HUMAN (8-861): 0: 1157: 83.49
+	Mm
		1174807 Q71LX8_MOUSE (1-504): 0: 673: 70.11		AGO2_MOUSE (5-861): 0: 1153: 78.19
+	Hs
		438614 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO2_HUMAN (12-861): 0: 1151: 78.94
+	Hs
		438537 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO3_HUMAN (5-861): 0: 1146: 81.18
+	Hs
		432356 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO1_HUMAN (8-861): 0: 1157: 83.49
+	Hs
		432355 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO2_HUMAN (12-861): 0: 1151: 78.94
+	Mm
		432448 HS90A_MOUSE (1-504): 0: 652: 61.81		AGO2_MOUSE (5-861): 0: 1153: 78.19
+	Hs
		432271 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO3_HUMAN (5-861): 0: 1146: 81.18
+	Hs
		1123444 H90B4_HUMAN (1-505): 0: 644: 100.00		AGO2_HUMAN (12-861): 0: 1151: 78.94
+	Hs
		1123440 H90B4_HUMAN (1-505): 0: 644: 100.00		AGO3_HUMAN (5-861): 0: 1146: 81.18
+	Dm
		365460 HSP83_DROME (1-504): 0: 669: 57.69		Q32KD4_DROME (5-861): 0: 1110: 70.68
+	Hs
		432159 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL1_HUMAN (17-828): 0: 739: 22.24
+	Dm
		365485 HSP83_DROME (1-504): 0: 669: 57.69		AGO2_DROME (21-819): 0: 693: 30.99
+	Hs
		432088 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL2_HUMAN (6-824): 0: 699: 22.24
+	Hs
		432003 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL4_HUMAN (21-824): 0: 672: 21.68
+	Dm
		365462 HSP83_DROME (1-504): 0: 669: 57.69		AGO3_DROME (21-828): 0: 609: 20.36
+	Dm
		365480 HSP83_DROME (1-504): 0: 669: 57.69		PIWI_DROME (21-819): 0: 557: 21.36
+	Hs
		431946 HS90A_HUMAN (1-504): 0: 655: 62.96		Q5TA56_HUMAN (5-208): 5.12e-93: 293: 67.14