HitPredict

Interactor 1: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Interactor 2: AGO1 (Q9UL18)
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
Gene: AGO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 857
+	Hs
		438615 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Mm
		1174807 Q71LX8_MOUSE (1-504): 0: 673: 70.11		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		432356 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		438614 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Mm
		432448 HS90A_MOUSE (1-504): 0: 652: 61.81		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		432355 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		438537 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		1123444 H90B4_HUMAN (1-505): 0: 644: 100.00		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		432271 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		438545 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		1123440 H90B4_HUMAN (1-505): 0: 644: 100.00		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Dm
		365460 HSP83_DROME (1-504): 0: 669: 57.69		Q32KD4_DROME (5-857): 0: 1153: 73.30
+	Hs
		432278 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		1123442 H90B4_HUMAN (1-505): 0: 644: 100.00		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		432159 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL1_HUMAN (18-824): 0: 733: 22.22
+	Dm
		365485 HSP83_DROME (1-504): 0: 669: 57.69		AGO2_DROME (28-816): 0: 714: 32.09
+	Hs
		432088 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL2_HUMAN (5-819): 0: 709: 21.77
+	Hs
		432003 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL4_HUMAN (18-820): 0: 675: 22.11
+	Dm
		365462 HSP83_DROME (1-504): 0: 669: 57.69		AGO3_DROME (29-824): 0: 621: 21.23
+	Hs
		431946 HS90A_HUMAN (1-504): 0: 655: 62.96		Q5TA56_HUMAN (3-216): 4.03e-99: 309: 67.71