HitPredict

Interactor 1: H90B3 (Q58FF7)
Putative heat shock protein HSP 90-beta-3 (Heat shock protein 90-beta c) (Heat shock protein 90Bc)
Gene: HSP90AB3P

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 597 Hs			1 530
+	Hs
		368839 HS90B_HUMAN (1-597): 0: 799: 75.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368832 HS90A_HUMAN (1-597): 0: 798: 66.67		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		320158 HS90B_HUMAN (1-597): 0: 799: 75.00		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		320155 HS90A_HUMAN (1-597): 0: 798: 66.67		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Mm
		415154 HS90B_MOUSE (1-597): 0: 802: 77.35		GCR_MOUSE (3-495): 7.76e-103: 328: 23.23
+	Hs
		377022 HS90B_HUMAN (1-597): 0: 799: 75.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377015 HS90A_HUMAN (1-597): 0: 798: 66.67		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Rn
		415133 HS90B_RAT (1-597): 0: 802: 77.35		GCR_RAT (3-495): 5.89e-100: 321: 23.03
+	Hs
		438124 HS90B_HUMAN (1-597): 0: 799: 75.00		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Hs
		431801 HS90A_HUMAN (1-597): 0: 798: 66.67		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Rn
		415141 HS90A_RAT (1-597): 0: 798: 66.17		GCR_RAT (3-495): 5.89e-100: 321: 23.03
+	Hs
		437901 HS90B_HUMAN (1-597): 0: 799: 75.00		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Gg
		430819 HS90B_CHICK (1-597): 0: 826: 72.14		PRGR_CHICK (149-408): 1.35e-39: 155: 33.58
+	Hs
		414418 HS90B_HUMAN (1-597): 0: 799: 75.00		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		414416 HS90A_HUMAN (1-597): 0: 798: 66.67		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Mm
		59437 HS90B_MOUSE (1-597): 0: 802: 77.35		A3KN90_MOUSE (141-408): 4.19e-38: 151: 34.51
+	Hs
		437625 HS90B_HUMAN (1-597): 0: 799: 75.00		MCR_HUMAN (141-408): 5.92e-38: 150: 34.03
+	Hs
		437831 HS90B_HUMAN (1-597): 0: 799: 75.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		431441 HS90A_HUMAN (1-597): 0: 798: 66.67		MCR_HUMAN (141-408): 5.92e-38: 150: 34.03
+	Hs
		431458 HS90A_HUMAN (1-597): 0: 798: 66.67		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59