HitPredict

Interactor 1: H90B3 (Q58FF7)
Putative heat shock protein HSP 90-beta-3 (Heat shock protein 90-beta c) (Heat shock protein 90Bc)
Gene: HSP90AB3P

Interactor 2: AGO3 (Q9H9G7)
Protein argonaute-3 (Argonaute3) (hAgo3) (EC 3.1.26.n2) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3)
Gene: AGO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 597 Hs			1 860
+	Hs
		438537 HS90B_HUMAN (1-597): 0: 799: 75.00		AGO3_HUMAN (1-860): 0: 1182: 100.00
+	Hs
		432271 HS90A_HUMAN (1-597): 0: 798: 66.67		AGO3_HUMAN (1-860): 0: 1182: 100.00
+	Hs
		438615 HS90B_HUMAN (1-597): 0: 799: 75.00		AGO1_HUMAN (9-860): 0: 1150: 84.62
+	Hs
		432356 HS90A_HUMAN (1-597): 0: 798: 66.67		AGO1_HUMAN (9-860): 0: 1150: 84.62
+	Mm
		1174807 Q71LX8_MOUSE (1-597): 0: 802: 77.35		AGO2_MOUSE (3-860): 0: 1144: 79.56
+	Hs
		438614 HS90B_HUMAN (1-597): 0: 799: 75.00		AGO2_HUMAN (15-860): 0: 1142: 80.73
+	Hs
		432355 HS90A_HUMAN (1-597): 0: 798: 66.67		AGO2_HUMAN (15-860): 0: 1142: 80.73
+	Mm
		432448 HS90A_MOUSE (1-597): 0: 796: 65.76		AGO2_MOUSE (3-860): 0: 1144: 79.56
+	Hs
		438545 HS90B_HUMAN (1-597): 0: 799: 75.00		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Hs
		432278 HS90A_HUMAN (1-597): 0: 798: 66.67		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Dm
		365460 HSP83_DROME (8-597): 0: 789: 60.67		Q32KD4_DROME (1-860): 0: 1102: 70.89
+	At
		138329 HS903_ARATH (10-597): 0: 748: 52.41		AGO1_ARATH (7-859): 0: 1064: 42.91
+	Ce
		108540 ENPL1_CAEEL (3-572): 0: 646: 33.97		G5EGR6_CAEEL (15-860): 0: 1074: 65.41
+	Hs
		432159 HS90A_HUMAN (1-597): 0: 798: 66.67		PIWL1_HUMAN (9-827): 0: 769: 21.57
+	Hs
		432088 HS90A_HUMAN (1-597): 0: 798: 66.67		PIWL2_HUMAN (5-822): 0: 710: 21.39
+	Dm
		365485 HSP83_DROME (8-597): 0: 789: 60.67		AGO2_DROME (22-820): 0: 696: 30.41
+	Hs
		432003 HS90A_HUMAN (1-597): 0: 798: 66.67		PIWL4_HUMAN (11-823): 0: 677: 20.96
+	Dm
		365462 HSP83_DROME (8-597): 0: 789: 60.67		AGO3_DROME (23-827): 0: 624: 20.05
+	Dm
		365480 HSP83_DROME (8-597): 0: 789: 60.67		PIWI_DROME (21-827): 0: 614: 21.64
+	Hs
		431946 HS90A_HUMAN (1-597): 0: 798: 66.67		Q5TA56_HUMAN (1-219): 4.81e-159: 464: 100.00