HitPredict

Interactor 1: H90B2 (Q58FF8)
Putative heat shock protein HSP 90-beta 2 (Heat shock protein 90-beta b) (Heat shock protein 90Bb)
Gene: HSP90AB2P

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005829 - cytosol GO:0006457 - protein folding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 381 Hs			1 494
+	Hs
		684789 H90B2_HUMAN (1-381): 2.81e-170: 482: 100.00		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		684788 H90B3_HUMAN (1-381): 8.64e-116: 350: 59.04		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		684791 HS904_HUMAN (57-381): 4.72e-80: 253: 37.27		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		174598 ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		684849 Q86SX1_HUMAN (1-136): 5.94e-78: 242: 68.79		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		538217 ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Ce
		183711 HSP90_CAEEL (200-381): 2.57e-57: 200: 55.62		STIP1_CAEEL (24-195): 7.35e-34: 131: 25.70
+	Hs
		538123 ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	At
		878278 HS902_ARATH (183-381): 3.49e-67: 226: 45.59		HSOP2_ARATH (2-362): 5.24e-14: 76.2: 14.25
+	Hs
		858647 Q86SX1_HUMAN (1-136): 5.94e-78: 242: 68.79		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		684790 HS905_HUMAN (108-355): 1.06e-55: 187: 60.08		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		684674 TRAP1_HUMAN (135-380): 3.01e-42: 158: 20.45		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Dm
		1361624 Q9VAY2_DROME (216-378): 4.52e-49: 178: 32.62		Q9VHA8_DROME (4-282): 8.56e-12: 69.3: 13.77
+	Hs
		858633 HS905_HUMAN (108-355): 1.06e-55: 187: 60.08		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		684787 H90B4_HUMAN (109-247): 1.76e-32: 129: 75.54		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Mm
		513680 HS90B_MOUSE (109-251): 9.78e-33: 131: 86.71		PPP5_MOUSE (139-260): 3.58e-16: 82.8: 13.93
+	Hs
		1123430 H90B4_HUMAN (109-247): 1.76e-32: 129: 75.54		DNJB3_HUMAN (381-485): 1.24e-16: 78.6: 40.68
+	Hs
		1162526 Q6PK50_HUMAN (109-251): 1.1e-33: 130: 87.41		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		1162522 Q6PK50_HUMAN (109-251): 1.1e-33: 130: 87.41		Q9BPW0_HUMAN (242-391): 8.91e-09: 59.7: 31.79
+	Hs
		858632 H90B4_HUMAN (109-247): 1.76e-32: 129: 75.54		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79