HitPredict

Interactor 1: HS905 (Q58FG0)
Putative heat shock protein HSP 90-alpha A5 (Heat shock protein 90-alpha E) (Heat shock protein 90Ae)
Gene: HSP90AA5P

Interactor 2: AGO3 (Q9H9G7)
Protein argonaute-3 (Argonaute3) (hAgo3) (EC 3.1.26.n2) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3)
Gene: AGO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Hs			1 860
+	Hs
		1123511 HS905_HUMAN (1-334): 1.88e-109: 323: 100.00		AGO1_HUMAN (9-860): 0: 1150: 84.62
+	Hs
		1123506 HS905_HUMAN (1-334): 1.88e-109: 323: 100.00		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Hs
		1123440 H90B4_HUMAN (22-280): 3.47e-71: 231: 33.53		AGO3_HUMAN (1-860): 0: 1182: 100.00
+	Hs
		1123445 H90B4_HUMAN (22-280): 3.47e-71: 231: 33.53		AGO1_HUMAN (9-860): 0: 1150: 84.62
+	Hs
		1123444 H90B4_HUMAN (22-280): 3.47e-71: 231: 33.53		AGO2_HUMAN (15-860): 0: 1142: 80.73
+	Hs
		1123442 H90B4_HUMAN (22-280): 3.47e-71: 231: 33.53		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Hs
		1123461 H90B3_HUMAN (230-330): 2.48e-21: 96.7: 40.78		AGO3_HUMAN (1-860): 0: 1182: 100.00
+	Hs
		438537 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		AGO3_HUMAN (1-860): 0: 1182: 100.00
+	Hs
		438615 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		AGO1_HUMAN (9-860): 0: 1150: 84.62
+	Mm
		1174807 Q71LX8_MOUSE (22-160): 9.09e-22: 98.2: 65.49		AGO2_MOUSE (3-860): 0: 1144: 79.56
+	Mm
		432448 HS90A_MOUSE (22-160): 8.73e-22: 98.2: 73.97		AGO2_MOUSE (3-860): 0: 1144: 79.56
+	Hs
		438614 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		AGO2_HUMAN (15-860): 0: 1142: 80.73
+	Dm
		1103835 Q9VAY2_DROME (22-160): 1.62e-31: 126: 35.25		Q32KD4_DROME (1-860): 0: 1102: 70.89
+	Hs
		438545 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Ce
		108540 ENPL1_CAEEL (22-160): 4.62e-23: 102: 25.90		G5EGR6_CAEEL (15-860): 0: 1074: 65.41
+	Hs
		1162519 Q6PK50_HUMAN (22-160): 1.23e-47: 165: 65.49		PIWL1_HUMAN (9-827): 0: 769: 21.57
+	Hs
		1162514 Q6PK50_HUMAN (22-160): 1.23e-47: 165: 65.49		PIWL2_HUMAN (5-822): 0: 710: 21.39
+	Hs
		1162506 Q6PK50_HUMAN (22-160): 1.23e-47: 165: 65.49		PIWL4_HUMAN (11-823): 0: 677: 20.96
+	Hs
		1135547 Q6PK50_HUMAN (22-160): 1.23e-47: 165: 65.49		Q5TA56_HUMAN (1-219): 4.81e-159: 464: 100.00
+	Hs
		431946 HS90A_HUMAN (22-160): 1.03e-17: 85.9: 75.17		Q5TA56_HUMAN (1-219): 4.81e-159: 464: 100.00