HitPredict

Interactor 1: HS905 (Q58FG0)
Putative heat shock protein HSP 90-alpha A5 (Heat shock protein 90-alpha E) (Heat shock protein 90Ae)
Gene: HSP90AA5P

Interactor 2: STK36 (Q9NRP7)
Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)
Gene: STK36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Hs			1 1315
+	Hs
		1123514 HS905_HUMAN (1-334): 1.88e-109: 323: 100.00		AKT3_HUMAN (1-327): 1.07e-125: 399: 28.44
+	Hs
		1123447 H90B4_HUMAN (22-280): 3.47e-71: 231: 33.53		AKT3_HUMAN (1-327): 1.07e-125: 399: 28.44
+	Hs
		1162538 Q6PK50_HUMAN (22-160): 1.23e-47: 165: 65.49		AKT3_HUMAN (1-327): 1.07e-125: 399: 28.44
+	Hs
		438146 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		KCC2B_HUMAN (2-503): 2.05e-128: 413: 24.58
+	Hs
		1123464 H90B3_HUMAN (230-330): 2.48e-21: 96.7: 40.78		AKT3_HUMAN (1-327): 1.07e-125: 399: 28.44
+	Mm
		432411 HS90A_MOUSE (22-160): 8.73e-22: 98.2: 73.97		AKT1_MOUSE (1-325): 6.76e-125: 397: 29.13
+	Hs
		437928 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		AKT2_HUMAN (1-328): 4.09e-126: 400: 28.36
+	Mm
		513660 HS90B_MOUSE (22-160): 9.09e-22: 98.2: 65.49		AKT1_MOUSE (1-325): 6.76e-125: 397: 29.13
+	Rn
		812703 HS90A_RAT (22-160): 8.65e-22: 98.2: 73.97		AKT1_RAT (1-325): 6.76e-125: 397: 29.13
+	Bt
		964601 HS90B_BOVIN (22-160): 8.99e-21: 95.2: 64.79		AKT1_BOVIN (1-325): 2.38e-126: 400: 29.43
+	Hs
		681885 H90B3_HUMAN (230-330): 2.48e-21: 96.7: 40.78		AKT1_HUMAN (1-325): 8.15e-125: 396: 29.43
+	Hs
		437927 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		AKT1_HUMAN (1-325): 8.15e-125: 396: 29.43
+	Hs
		1123513 HS905_HUMAN (1-334): 1.88e-109: 323: 100.00		AURKC_HUMAN (1-264): 7.61e-45: 166: 36.33
+	Hs
		438147 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		KCC2G_HUMAN (2-468): 3.25e-122: 392: 24.32
+	Hs
		1123505 HS905_HUMAN (1-334): 1.88e-109: 323: 100.00		SGK2_HUMAN (4-243): 2.39e-41: 158: 36.18
+	Hs
		1123413 H90B4_HUMAN (22-280): 3.47e-71: 231: 33.53		ULK3_HUMAN (1-270): 2.66e-42: 164: 37.72
+	Hs
		1123441 H90B4_HUMAN (22-280): 3.47e-71: 231: 33.53		SGK2_HUMAN (4-243): 2.39e-41: 158: 36.18
+	Hs
		1123463 H90B3_HUMAN (230-330): 2.48e-21: 96.7: 40.78		AURKC_HUMAN (1-264): 7.61e-45: 166: 36.33
+	Hs
		116958 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		SGK1_HUMAN (4-311): 3.14e-43: 166: 33.33
+	Hs
		438277 HS90B_HUMAN (22-160): 8.04e-21: 95.2: 64.79		ULK3_HUMAN (1-270): 2.66e-42: 164: 37.72