HitPredict

Interactor 1: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Interactor 2: SGK3 (Q96BR1)
Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)
Gene: SGK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 496
+	Hs
		1123562 HS904_HUMAN (1-418): 0: 547: 100.00		AKT3_HUMAN (20-493): 9.6e-167: 481: 38.27
+	Hs
		1123553 HS904_HUMAN (1-418): 0: 547: 100.00		SGK2_HUMAN (129-495): 2.69e-152: 440: 66.76
+	Hs
		969092 H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81		KPCE_HUMAN (1-487): 1.02e-152: 454: 30.26
+	Hs
		1123464 H90B3_HUMAN (2-153): 1.55e-48: 175: 50.66		AKT3_HUMAN (20-493): 9.6e-167: 481: 38.27
+	Hs
		681885 H90B3_HUMAN (2-153): 1.55e-48: 175: 50.66		AKT1_HUMAN (20-491): 1.46e-165: 478: 36.48
+	Hs
		431548 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCL_HUMAN (1-493): 1.44e-164: 483: 31.72
+	Hs
		431572 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AKT1_HUMAN (20-491): 1.46e-165: 478: 36.48
+	Hs
		431762 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCT_HUMAN (1-496): 2.35e-162: 478: 28.25
+	Hs
		431573 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AKT2_HUMAN (20-490): 5.54e-165: 477: 36.63
+	Hs
		431767 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCD_HUMAN (1-496): 4.95e-161: 473: 29.74
+	Hs
		116956 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		SGK1_HUMAN (86-495): 2e-162: 468: 66.34
+	Hs
		431752 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCE_HUMAN (1-487): 1.02e-152: 454: 30.26
+	Hs
		431510 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCA_HUMAN (42-490): 3.95e-147: 438: 33.55
+	Hs
		431542 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KS6B1_HUMAN (78-491): 3.96e-148: 435: 38.33
+	Hs
		431621 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCI_HUMAN (14-490): 3.77e-147: 435: 32.72
+	Hs
		850666 H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81		KS6A3_HUMAN (48-466): 8.02e-109: 341: 23.72
+	Hs
		1073431 H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81		KS6A1_HUMAN (47-423): 1.85e-95: 306: 27.32
+	Hs
		431672 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KS6A3_HUMAN (48-466): 8.02e-109: 341: 23.72
+	Hs
		431876 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KS6A1_HUMAN (47-423): 1.85e-95: 306: 27.32
+	Hs
		431766 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCZ_HUMAN (161-458): 1.09e-90: 290: 45.60