HitPredict

Interactor 1: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Interactor 2: SGK2 (Q9HBY8)
Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)
Gene: SGK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 367
+	Hs
		1123562 HS904_HUMAN (1-418): 0: 547: 100.00		AKT3_HUMAN (1-359): 6.48e-151: 436: 47.66
+	Hs
		1123539 HS904_HUMAN (1-418): 0: 547: 100.00		SGK3_HUMAN (9-364): 7.87e-146: 423: 67.69
+	Hs
		270422 HS904_HUMAN (1-418): 0: 547: 100.00		KS6A5_HUMAN (12-294): 6.28e-99: 312: 26.17
+	Hs
		969092 H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81		KPCE_HUMAN (6-362): 3.33e-146: 432: 41.67
+	Hs
		431548 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCL_HUMAN (13-363): 1.31e-151: 444: 41.64
+	Hs
		1123464 H90B3_HUMAN (2-153): 1.55e-48: 175: 50.66		AKT3_HUMAN (1-359): 6.48e-151: 436: 47.66
+	Hs
		681885 H90B3_HUMAN (2-153): 1.55e-48: 175: 50.66		AKT1_HUMAN (6-359): 3.45e-151: 436: 47.62
+	Hs
		116956 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		SGK1_HUMAN (3-365): 9.63e-154: 441: 68.73
+	Hs
		431573 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AKT2_HUMAN (5-359): 4.08e-153: 441: 47.06
+	Hs
		431572 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AKT1_HUMAN (6-359): 3.45e-151: 436: 47.62
+	Hs
		431752 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCE_HUMAN (6-362): 3.33e-146: 432: 41.67
+	Hs
		431762 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCT_HUMAN (24-365): 1.64e-146: 432: 40.06
+	Hs
		431542 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KS6B1_HUMAN (4-361): 3.11e-145: 422: 42.15
+	Hs
		1073431 H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81		KS6A1_HUMAN (13-338): 1.87e-104: 325: 25.52
+	Hs
		850666 H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81		KS6A3_HUMAN (25-335): 1.1e-104: 325: 25.47
+	Hs
		431672 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KS6A3_HUMAN (25-335): 1.1e-104: 325: 25.47
+	Hs
		431873 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KS6A2_HUMAN (7-335): 7.98e-102: 318: 25.88
+	Hs
		270363 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KS6A5_HUMAN (12-294): 6.28e-99: 312: 26.17
+	Hs
		431621 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCI_HUMAN (34-340): 2.85e-99: 307: 46.23
+	Hs
		431766 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		KPCZ_HUMAN (34-357): 1.99e-96: 300: 45.21