HitPredict

Interactor 1: Q59EL4 (Q59EL4)
PRPF4 protein variant
Gene: Q59EL4

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 2527
+	Hs
		903286 WDR5_HUMAN (53-407): 7.45e-69: 226: 12.50		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		792995 LIS1_HUMAN (64-368): 3.23e-59: 203: 11.39		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130725 PRP19_HUMAN (131-493): 4.76e-17: 85.9: 22.49		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130429 SNR40_HUMAN (456-537): 1.56e-15: 80: 28.92		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		48975 A0MNP2_HUMAN (456-537): 1.56e-15: 80: 28.92		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		921599 GBB2_HUMAN (249-450): 2.96e-14: 75.9: 26.96		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1281479 FBXW7_HUMAN (14-403): 9.86e-54: 195: 13.07		SHOC2_HUMAN (944-1353): 1.23e-60: 222: 22.27
+	Hs
		201387 FBXW7_HUMAN (14-403): 9.86e-54: 195: 13.07		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	Hs
		201412 TBL1Y_HUMAN (3-367): 8.58e-55: 194: 15.43		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83