HitPredict

Interactor 1: RASF5 (Q5EBH1)
Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)
Gene: Rassf5

Interactor 2: RASH (Q61411)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: Hras

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.80	0.729

Property	Details
Experiments	18596699, 9488663
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	C1_1~Ras, RA~Ras
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 413 Mm			1 189
+	Hs
		350400 RASF5_HUMAN (1-413): 0: 557: 85.10		RASK_HUMAN (1-188): 2.04e-84: 248: 86.24
+	Mm
		1125491 RASF5_MOUSE (1-413): 0: 581: 100.00		RAP1B_MOUSE (1-165): 2.18e-63: 195: 57.49
+	Hs
		349532 RASF5_HUMAN (1-413): 0: 557: 85.10		RASH_HUMAN (16-189): 5.68e-73: 219: 100.00
+	Hs
		897926 RASF5_HUMAN (1-413): 0: 557: 85.10		RAP1B_HUMAN (1-165): 2.18e-63: 195: 57.49
+	Hs
		919655 RASF5_HUMAN (1-413): 0: 557: 85.10		RAP1A_HUMAN (1-165): 3.2e-62: 192: 56.89
+	Hs
		349676 RASF1_HUMAN (82-405): 1.5e-140: 406: 45.56		RASH_HUMAN (16-189): 5.68e-73: 219: 100.00
+	Hs
		349983 RASF2_HUMAN (245-413): 6.48e-54: 183: 28.49		RASK_HUMAN (1-188): 2.04e-84: 248: 86.24
+	Hs
		349196 RASF2_HUMAN (245-413): 6.48e-54: 183: 28.49		RASH_HUMAN (16-189): 5.68e-73: 219: 100.00