HitPredict

Interactor 1: ESCO1 (Q5FWF5)
N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1)
Gene: ESCO1

Interactor 2: CBX8 (Q9HC52)
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)
Gene: CBX8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 389
+	Hs
		203701 ESCO1_HUMAN (1-840): 0: 608: 100.00		SUV91_HUMAN (11-102): 9.92e-27: 112: 25.25
+	Hs
		1122702 ESCO2_HUMAN (322-833): 2e-123: 386: 35.96		CBX8_HUMAN (1-389): 5.01e-104: 314: 100.00
+	Hs
		203700 ESCO2_HUMAN (322-833): 2e-123: 386: 35.96		SUV91_HUMAN (11-102): 9.92e-27: 112: 25.25
+	Hs
		123328 MDN1_HUMAN (5-608): 9.4e-12: 71.4: 10.67		CBX4_HUMAN (1-349): 3.84e-62: 210: 21.93
+	Hs
		1059197 MDN1_HUMAN (5-608): 9.4e-12: 71.4: 10.67		CBX2_HUMAN (2-348): 3.75e-46: 167: 22.03
+	Dm
		639982 Q9W1A9_DROME (12-428): 5.44e-09: 62.5: 11.27		PC_DROME (10-388): 2.97e-47: 167: 21.99