HitPredict

Interactor 1: HERC4 (Q5GLZ8)
Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4)
Gene: HERC4

Interactor 2: HERC4 (Q5GLZ8)
Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4)
Gene: HERC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 26949039, 22496338
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HECT~HECT, RCC1~RCC1
Common GO terms GO:0001650 - fibrillar center
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0007283 - spermatogenesis
and 4 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1057
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024