HitPredict

Interactor 1: HERC4 (Q5GLZ8)
Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4)
Gene: HERC4

Interactor 2: WRP73 (Q9P2S5)
WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)
Gene: WRAP73

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1057 Hs			1 460
+	Hs
		125414 WWP2_HUMAN (374-1055): 0: 619: 20.66		TBL3_HUMAN (59-460): 2.55e-51: 187: 12.50
+	Hs
		125310 WWP2_HUMAN (374-1055): 0: 619: 20.66		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		903156 UBE3A_HUMAN (442-1057): 5.58e-173: 531: 29.50		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Sc
		635632 TOM1_YEAST (707-1056): 1.91e-49: 194: 32.23		PWP2_YEAST (291-459): 8.52e-15: 79: 11.24
+	Sc
		561903 TOM1_YEAST (707-1056): 1.91e-49: 194: 32.23		TUP1_YEAST (82-363): 5.33e-10: 63.7: 12.71