HitPredict

Interactor 1: BCORL (Q5H9F3)
BCL-6 corepressor-like protein 1 (BCoR-L1) (BCoR-like protein 1)
Gene: BCORL1

Interactor 2: RYBP (Q8N488)
RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1)
Gene: RYBP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	24981860, 26186194, 28514442, 27705803, 33961781, 22325352
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1785 Hs			1 228
+	Hs
		1125887 BCORL_HUMAN (1-1785): 7.14e-132: 456: 100.00		YAF2_HUMAN (3-227): 3.24e-55: 176: 52.89
+	Hs
		1167270 BCOR_HUMAN (1-1780): 6.52e-94: 340: 21.03		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Hs
		1167267 BCOR_HUMAN (1-1780): 6.52e-94: 340: 21.03		YAF2_HUMAN (3-227): 3.24e-55: 176: 52.89
+	Hs
		166966 ANR28_HUMAN (1200-1619): 1.05e-56: 217: 12.28		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Hs
		1205982 MIB1_HUMAN (1269-1645): 3.5e-45: 180: 14.68		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Dr
		1092814 MIB1_DANRE (1462-1764): 2.14e-48: 191: 18.36		Q1JPU4_DANRE (3-227): 4.18e-56: 178: 53.78
+	Hs
		1233096 ANR44_HUMAN (1566-1785): 2.56e-40: 165: 9.33		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Dm
		1214939 Q8IQT4_DROME (187-646): 1.63e-09: 65.3: 16.73		Q9W215_DROME (3-197): 3.06e-42: 142: 37.95