HitPredict

Interactor 1: PP6R3 (Q5H9R7)
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)
Gene: PPP6R3

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 873 Hs			1 347
+	Hs
		257226 PP6R2_HUMAN (1-870): 0: 766: 45.79		SHLB2_HUMAN (10-342): 1.05e-58: 196: 20.57
+	Hs
		1307463 PP6R1_HUMAN (1-872): 0: 670: 44.00		SH3G3_HUMAN (1-347): 9.83e-90: 274: 100.00
+	Hs
		1307441 PP6R1_HUMAN (1-872): 0: 670: 44.00		SH3G2_HUMAN (1-347): 8.3e-86: 264: 65.91
+	Hs
		924616 PP6R3_HUMAN (1-873): 0: 854: 100.00		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Rn
		192356 SYNJ1_RAT (459-866): 2.81e-34: 144: 11.34		SH3G3_RAT (1-346): 1.05e-86: 266: 86.99
+	Rn
		192354 SYNJ1_RAT (459-866): 2.81e-34: 144: 11.34		SH3G2_RAT (1-347): 3.62e-85: 262: 65.63
+	Hs
		203249 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		SH3G2_HUMAN (1-347): 8.3e-86: 264: 65.91
+	Rn
		193638 SYNJ1_RAT (459-866): 2.81e-34: 144: 11.34		SH3G1_RAT (1-347): 1.14e-78: 246: 66.30
+	Hs
		203248 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		SH3G1_HUMAN (1-347): 7.8e-80: 249: 66.30
+	Mm
		88459 D3Z656_MOUSE (560-868): 2.99e-09: 63: 11.00		SH3G2_MOUSE (1-347): 4.35e-85: 262: 65.63
+	Hs
		1052365 CABIN_HUMAN (613-873): 2.13e-24: 112: 14.56		SRC8_HUMAN (7-343): 2.64e-50: 177: 14.49
+	Hs
		203262 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		PACN2_HUMAN (1-343): 3.2e-38: 143: 16.45
+	Hs
		203246 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		SH3Y1_HUMAN (139-341): 5.08e-38: 140: 19.73
+	Hs
		203251 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		PACN1_HUMAN (6-342): 5.44e-34: 131: 14.90
+	Rn
		192744 SYNJ1_RAT (459-866): 2.81e-34: 144: 11.34		SRBS2_RAT (243-342): 7.4e-12: 68.5: 21.57
+	Hs
		203250 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		SRBS1_HUMAN (169-342): 1.13e-13: 74.1: 17.65
+	Hs
		203228 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		ITSN1_HUMAN (253-341): 7.42e-12: 68.9: 23.60
+	Hs
		203218 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		203192 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		SRBS2_HUMAN (291-344): 2.01e-10: 64.3: 48.15
+	Hs
		203230 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		SH319_HUMAN (291-342): 6.81e-09: 59.3: 48.08