Interactor 1: EMC4 (Q5J8M3)
ER membrane protein complex subunit 4 (Cell proliferation-inducing gene 17 protein) (Transmembrane protein 85)
Gene: EMC4

Interactor 2: EMC3 (Q9P0I2)
ER membrane protein complex subunit 3 (Transmembrane protein 111)
Gene: EMC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 22119785, 28514442, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF1077~EMC3_TMCO1
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0034975 - protein folding in endoplasmic reticulum
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 183
Hs

1 261
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024