Interactor 1: M9NE13 (M9NE13)
Nicotinic acetylcholine receptor alpha4, isoform D (Nicotinic acetylcholine receptor alpha4, isoform F)
Gene: nAChRalpha4

Interactor 2: Q9VPQ8 (Q9VPQ8)
Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit (Nicotinic acetylcholine receptor beta subunit) (Nicotinic acetylcholine receptor beta3)
Gene: nAChRbeta3

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11953451
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0004888 - transmembrane signaling receptor activity
GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0007271 - synaptic transmission, cholinergic
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 371
Dm

1 441
+ Hs
+ Mm
+ Gg
+ Gg
+ Hs
+ Gg
+ Gg
+ Gg
+ Dm
+ Dm
+ Rn
+ Hs
+ Hs
+ Dm
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+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024