HitPredict

Interactor 1: MTUS2 (Q5JR59)
Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)
Gene: MTUS2

Interactor 2: Q6IPE9 (Q6IPE9)
MARK4 protein (Microtubule affinity regulating kinase 4)
Gene: MARK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1369 Hs			1 97
+	Hs
		1127116 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		MARK4_HUMAN (1-96): 8.02e-51: 171: 84.54
+	Hs
		871403 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		AAPK2_HUMAN (1-96): 2.53e-50: 167: 51.55
+	Hs
		681887 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		AKT1_HUMAN (1-97): 1.87e-45: 153: 39.00
+	Hs
		725223 MYH10_HUMAN (928-1347): 4.52e-17: 89.6: 16.17		MARK4_HUMAN (1-96): 8.02e-51: 171: 84.54
+	Hs
		724967 MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70		MARK4_HUMAN (1-96): 8.02e-51: 171: 84.54
+	Hs
		116964 MYH1_HUMAN (698-1170): 2.35e-14: 81: 7.93		SGK1_HUMAN (2-94): 3.04e-44: 149: 38.95
+	Hs
		551616 DESP_HUMAN (972-1329): 6.4e-13: 76: 15.94		AKT1_HUMAN (1-97): 1.87e-45: 153: 39.00
+	Hs
		681696 MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70		AKT1_HUMAN (1-97): 1.87e-45: 153: 39.00
+	Hs
		725242 MYH10_HUMAN (928-1347): 4.52e-17: 89.6: 16.17		SIK2_HUMAN (18-95): 1.2e-32: 120: 67.95
+	Hs
		725010 MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70		SIK2_HUMAN (18-95): 1.2e-32: 120: 67.95
+	Hs
		728513 MYH11_HUMAN (1079-1362): 3.25e-10: 67.2: 9.83		SIK2_HUMAN (18-95): 1.2e-32: 120: 67.95