Interactor 1: DOC11 (Q5JSL3)
Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)
Gene: DOCK11
Interactor 2: DOCK9 (Q9BZ29)
Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1)
Gene: DOCK9
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.66 | 1.00 | 0.817 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, 35271311, unassigned2213 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DHR-2_Lobe_A~DHR-2_Lobe_A, DHR-2_Lobe_A~DHR-2_Lobe_B, DHR-2_Lobe_B~DHR-2_Lobe_C, DHR-2_Lobe_C~DHR-2_Lobe_C, DOCK-C2~DOCK-C2, PH~PH |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005829 - cytosol GO:0007264 - small GTPase-mediated signal transduction GO:0043547 - positive regulation of GTPase activity |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | At | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
