Interactor 1: FGD3 (Q5JSP0)
FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5)
Gene: FGD3

Interactor 2: RHG22 (Q7Z5H3)
Rho GTPase-activating protein 22 (Rho-type GTPase-activating protein 22)
Gene: ARHGAP22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 32203420, unassigned2213
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PH, PH~RhoGEF
Common GO terms GO:0005829 - cytosol
GO:0051056 - regulation of small GTPase mediated signal transduction
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 725
Hs

1 698
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024