Interactor 1: FGD3 (Q5JSP0)
FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5)
Gene: FGD3

Interactor 2: FGD4 (Q96M96)
FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)
Gene: FGD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE~FYVE, PH~PH, PH~RhoGEF, RhoGEF~RhoGEF
Common GO terms GO:0001726 - ruffle
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
and 10 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 725
Hs

1 766
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Last updated: 15 Jul 2024