HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2229 Hs			1 482
+	Hs
		1030280 PRC2B_HUMAN (1-2229): 0: 619: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1127664 PRC2B_HUMAN (1-2229): 0: 619: 100.00		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1357447 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1049678 EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		821086 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1030574 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030230 EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		820907 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1272144 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		820996 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		311338 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		CELF2_HUMAN (309-419): 2e-14: 77.2: 18.10