HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: YTHD2 (Q9Y5A9)
YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)
Gene: YTHDF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 2229 Hs			1 579
+	Hs
		1127634 PRC2B_HUMAN (1-2229): 0: 619: 100.00		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		1127688 PRC2B_HUMAN (1-2229): 0: 619: 100.00		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		1377926 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		YTHD2_HUMAN (1-579): 1.24e-177: 516: 100.00
+	Hs
		1301022 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		YTHD2_HUMAN (1-579): 1.24e-177: 516: 100.00
+	Hs
		821100 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		YTHD2_HUMAN (1-579): 1.24e-177: 516: 100.00
+	Hs
		1192419 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		1317062 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		820960 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		821029 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		1300943 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		YTDC2_HUMAN (285-556): 1.53e-54: 202: 20.50
+	Hs
		867119 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		SC24C_HUMAN (42-405): 4.03e-36: 146: 15.51
+	Dm
		113976 M9PB30_DROME (1183-1955): 1.05e-13: 79.8: 9.22		M9PB30_DROME (1-283): 4.63e-15: 81.1: 9.39
+	Mm
		1351630 PCLO_MOUSE (15-1858): 1.65e-14: 82.4: 8.18		PCLO_MOUSE (39-306): 1.24e-09: 63.8: 14.49